Vittorio Pace, Fernando Martınez, Clara I. Nova, Marıa Fernández, José Vicente Sinisterra and Andrés R. AlcántaraDepartment of Organic and Pharmaceutical Chemistry, Pharmacy Faculty, Complutense University, Pza. Ramón y Cajal s/n, 28040 Madrid Spain
Industrial Biotransformations Service (SBI), Scientific Park of Madrid (PTM), C/ Santiago Grisolia 2, 28760 Tres Cantos, Madrid Spain
Abstract
An intramolecular Horner-Wadsworth-Emmons reaction promoted by KF-Alumina involving a N-substituted phthalimide, cleanly and efficiently furnishes an interesting α,β-unsaturated tricyclic enone which may undergo selective alkylations at the α’-position.
An intramolecular Horner-Wadsworth-Emmons reaction promoted by KF-Alumina involving a N-substituted phthalimide, cleanly and efficiently furnishes an interesting α,β-unsaturated tricyclic enone which may undergo selective alkylations at the α’-position.
Entradas
